Review
doi: 10.1016/s0168-9525(97)01246-8.
Sunlight and the onset of skin cancer
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- PMID: 9351343
- DOI: 10.1016/s0168-9525(97)01246-8
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Review
Sunlight and the onset of skin cancer
Trends Genet.
1997 Oct.
Free article
Abstract
The photons of sunlight precipitate a series of genetic events in skin leading to cancer. These events involve somatic mutations as well as inherited alleles. Competition between cell populations ensues, as a single mutated cell expands into a clone. Thus cancer involves both a single-cell problem and a many-cell problem; in skin cancer, sunlight appears to drive both.
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