Clinical Trial
doi: 10.1017/s0033291700007509.
The endogenous--neurotic distinction as a predictor of response to antidepressant drugs
- PMID: 935298
- DOI: 10.1017/s0033291700007509
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Clinical Trial
The endogenous--neurotic distinction as a predictor of response to antidepressant drugs
Psychol Med.
1976 Feb.
Abstract
An inverse factor analysis of 880 depressed inpatients on 33 endogenous-neurotic variables yielded four patient types. Type 3 resembled the endogenous depressions and Type 2 the neurotic depressions. Type 3 patients responded well to both imipramine and chlorpromazine and did poorly on a placebo. Type 2 patients showed the greatest overall improvement at three weeks irrespective of treatment received, including a placebo.
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