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Review
. 1997 Nov 11;94(23):12251-4.
doi: 10.1073/pnas.94.23.12251.

Archaeal chromatin: virtual or real?

Affiliations
Review

Archaeal chromatin: virtual or real?

J Zlatanova. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
The universal phylogenetic tree, as seen by Woese and collaborators (adapted from ref. 2), showing the three domains. The branching order and branch lengths are derived from sequence comparisons of rRNA. The branches pointing to different lineages of organisms are presented only for the domain Archaea. ∗ Denotes archaeal groups known to contain proteins homologous to eucaryal core histones (note that none have been so far reported for kingdom Crenarchaeota). + Denotes groups in which chromatin-like organization has been directly visualized by electron microscopy (EM).
Figure 2
Figure 2
(A) Ribbon representation of the three-dimensional fold of recombinant HMfB monomer (Left) (NMR structure, ref. 19), compared with that of the structured portion of chicken core histone H4 (Right) (crystal structure, ref. 20). Roman numerals denote helices I, II, and III, respectively. The similarity of structures is remarkable. (B) Ribbon model of a dimer of HMfB molecules, presenting the two monomers in the “handshake motif” typical of core histone heterodimers H2A-H2B and H3 and H4 (19, 20). Both images courtesy of M. Summers (University of Maryland, Baltimore).

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