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. 1997 Nov;4(11):891-5.
doi: 10.1038/nsb1197-891.

A novel RNA-binding motif in influenza A virus non-structural protein 1

C Y Chien, R Tejero, Y Huang, D E Zimmerman, C B Ríos, R M Krug, G T Montelione

A novel RNA-binding motif in influenza A virus non-structural protein 1

C Y Chien et al. Nat Struct Biol. 1997 Nov.

Abstract

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold. Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.

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