Nosocomial pneumonia

Abstract

Nosocomial pneumonia remains a major cause of morbidity, mortality, and significant hospital cost despite continued refinements in antimicrobial treatment, improved methods for diagnosis, and better supportive and preventive measures. While clinical experience is considerable, appreciation of the epidemiologic and pathogenic factors responsible for NP development and pathogen selection are limited, and consensus regarding optimal prevention and diagnostic and therapeutic strategies is lacking. This article reviews the recent literature with an emphasis on significance, pathogenesis, etiology, and therapy of nosocomial pneumonia.