Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1997 Oct;31(4):318-23.
doi: 10.1046/j.1365-2559.1997.1610866.x.

Gastrointestinal tumour masses due to multiple myeloma: a pathological mimic of malignant lymphoma

A P Griffiths  1 , N A Shepherd, A Beddall, J G Williams
Affiliations
Case Reports

Gastrointestinal tumour masses due to multiple myeloma: a pathological mimic of malignant lymphoma

A P Griffiths et al. Histopathology. 1997 Oct.

Abstract

Aims: To describe and evaluate two cases of gastrointestinal involvement by multiple myeloma.

Methods and results: Clinical details were obtained from patients records and routine histopathological sections were correlated with haematological and immunohistochemical investigations. As shown in the accompanying illustrations, myeloma manifests as large, atypical, non-cohesive cells which may mimic high-grade lymphoma.

Conclusions: Extraskeletal spread of multiple myeloma occurs more frequently than is currently recognized, but clinical involvement of gut is rarely reported. Gut involvement may occur soon after initial diagnosis of myeloma and may be of serious clinical consequence. Histologically, it may mimic high-grade lymphoma. Failure to recognize myelomatous involvement of gut may result in inappropriate surgery or oncological therapy.

PubMed Disclaimer

Publication types