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Case Reports
. 1997 Mar-Apr;10(2):237-41.
doi: 10.1515/jpem.1997.10.2.237.

Recovery from metabolic bone disease in a girl with vitamin D deficiency rickets associated with primary hyperparathyroidism

R Luboshitzky  1 , R Hardoff
Affiliations
Case Reports

Recovery from metabolic bone disease in a girl with vitamin D deficiency rickets associated with primary hyperparathyroidism

R Luboshitzky et al. J Pediatr Endocrinol Metab. 1997 Mar-Apr.

Abstract

We describe a 13 year-old Ethiopian girl with vitamin D deficiency rickets. Hypercalcemia, increased serum alkaline phosphatase and PTH levels, together with low serum levels of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D suggested the co-existence of primary hyperparathyroidism. The surgical removal of a parathyroid adenoma led to bone healing and normalization of blood chemistry. We conclude that vitamin D deficiency masked the hyperparathyroidism and hypercalcemia, while excess PTH secretion delayed the cure of rickets until successful parathyroidectomy had been carried out.

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