Overexpression of A-myb induces basic fibroblast growth factor-dependent proliferation of chicken neuroretina cells
- PMID: 9371644
- PMCID: PMC230288
- DOI: 10.1128/JVI.71.12.9778-9781.1997
Overexpression of A-myb induces basic fibroblast growth factor-dependent proliferation of chicken neuroretina cells
Abstract
A-Myb behaves similarly to c-Myb in chicken neuroretina cells in its ability to induce fibroblast-like differentiation, to promote growth in the presence of basic fibroblast growth factor (bFGF), and to induce Pax-6 and mim-1 expression. The one difference between c-Myb and A-Myb in these cells is that the former but not the latter protein causes colony formation in soft agar in the presence of bFGF.
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