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. 1997 Sep 30;94(20):10493-5.
doi: 10.1073/pnas.94.20.10493.

Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity

Affiliations

Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity

M F Goodman. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Geometric properties of Watson–Crick and mismatched base pairs. This figure is based on x-ray crystallography of duplex B-DNA oligonucleotides. The striking geometric identity of the Watson–Crick A⋅T and G⋅C base pairs is not matched by the A⋅C protonated wobble and G⋅T wobble base mispairs or by the G(anti)⋅A(syn) base mispair. [Reproduced with permission from ref. (copyright 1987, Springer, Heidelberg).]

References

    1. Schweitzer B A, Kool E T. J Org Chem. 1994;59:7238–7242. - PMC - PubMed
    1. Moran S, Ren R X-F, Kool E T. Proc Natl Acad Sci USA. 1997;94:10506–10511. - PMC - PubMed
    1. Moran S, Ren R X-F, Rumney S, Kool E T. J Am Chem Soc. 1997;119:2056–2057. - PMC - PubMed
    1. Aboul-ela F, Koh D, Tinoco I J, Martin F H. Nucleic Acids Res. 1985;13:4811–4825. - PMC - PubMed
    1. Petruska J, Goodman M F, Boosalis M S, Sowers L C, Cheong C, Tinoco I., Jr Proc Natl Acad Sci USA. 1988;85:6252–6256. - PMC - PubMed

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