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Review
. 1997 Dec 1;7(12):R789-92.
doi: 10.1016/s0960-9822(06)00406-4.

Cell-cycle signaling: Atm displays its many talents

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Free article
Review

Cell-cycle signaling: Atm displays its many talents

C H Westphal. Curr Biol. .
Free article

Abstract

The discovery of multiple signaling cascades downstream of Atm may lead to a clearer understanding of the diverse defects seen in ataxia-telangiectasia. These pathways - which include evolutionarily conserved Chk1 and Atr, and non-conserved p21, p53 and AbI - guard genomic integrity after DNA damage.

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