Review
doi: 10.1016/s0960-9822(06)00401-5.
PDZ domain proteins: scaffolds for signaling complexes
Affiliations
- PMID: 9382826
- DOI: 10.1016/s0960-9822(06)00401-5
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Review
PDZ domain proteins: scaffolds for signaling complexes
Curr Biol.
.
Free article
Abstract
InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
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