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Review
. 1997 Dec 1;7(12):R763-7.
doi: 10.1016/s0960-9822(06)00399-x.

Toxin structure: part of a hole?

H Bayley  1
Affiliations
Free article
Review

Toxin structure: part of a hole?

H Bayley. Curr Biol. .
Free article

Abstract

The structure of the monomeric form of perfringolysin O solved by X-ray crystallography has been used to model the very large transmembrane pore formed when this bacterial protein toxin assembles in cholesterol-containing membranes. The structure is a notable advance, but it may not provide the whole story.

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