Evolution in action
- PMID: 9383406
- DOI: 10.1016/1074-5521(95)90278-3
Evolution in action
Abstract
The alpha/beta barrel enzyme phosphotriesterase from soil bacteria appears to have evolved the ability to hydrolyze the insecticide paraoxon at the diffusion limit in only a few decades. A newly-identified open reading frame from Escherichia coli may offer a clue to its origins.
Similar articles
-
A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase.Biochemistry. 1997 Jan 28;36(4):786-95. doi: 10.1021/bi961412g. Biochemistry. 1997. PMID: 9020776
-
Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source.Appl Environ Microbiol. 2004 Jan;70(1):404-12. doi: 10.1128/AEM.70.1.404-412.2004. Appl Environ Microbiol. 2004. PMID: 14711669 Free PMC article.
-
Phosphotriesterase: an enzyme in search of its natural substrate.Adv Enzymol Relat Areas Mol Biol. 2000;74:51-93. doi: 10.1002/9780470123201.ch2. Adv Enzymol Relat Areas Mol Biol. 2000. PMID: 10800593 Review.
-
Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family.Biochemistry. 1998 Apr 14;37(15):5096-106. doi: 10.1021/bi971707+. Biochemistry. 1998. PMID: 9548740
-
Soil-based gene discovery: a new technology to accelerate and broaden biocatalytic applications.Adv Appl Microbiol. 2003;52:1-27. doi: 10.1016/s0065-2164(03)01001-3. Adv Appl Microbiol. 2003. PMID: 12964238 Review. No abstract available.
Cited by
-
A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase.J Mol Biol. 2008 Mar 21;377(2):323-36. doi: 10.1016/j.jmb.2008.01.043. Epub 2008 Jan 26. J Mol Biol. 2008. PMID: 18272177 Free PMC article.
-
Enhancing the promiscuous phosphotriesterase activity of a thermostable lactonase (GkaP) for the efficient degradation of organophosphate pesticides.Appl Environ Microbiol. 2012 Sep;78(18):6647-55. doi: 10.1128/AEM.01122-12. Epub 2012 Jul 13. Appl Environ Microbiol. 2012. PMID: 22798358 Free PMC article.
-
Vaccinia virus J1R protein: a viral membrane protein that is essential for virion morphogenesis.J Virol. 2002 Oct;76(19):9575-87. doi: 10.1128/jvi.76.19.9575-9587.2002. J Virol. 2002. PMID: 12208937 Free PMC article.
-
The origin of genetic and metabolic systems: Evolutionary structuralinsights.Heliyon. 2023 Mar 11;9(3):e14466. doi: 10.1016/j.heliyon.2023.e14466. eCollection 2023 Mar. Heliyon. 2023. PMID: 36967965 Free PMC article.
-
Multiple mechanisms contribute to lateral transfer of an organophosphate degradation (opd) island in Sphingobium fuliginis ATCC 27551.G3 (Bethesda). 2012 Dec;2(12):1541-54. doi: 10.1534/g3.112.004051. Epub 2012 Dec 1. G3 (Bethesda). 2012. PMID: 23275877 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources