Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996;2(1):5-14.
doi: 10.1007/BF00128467.

Using the EM-algorithm for survival data with incomplete categorical covariates

S R Lipsitz  1 , J G Ibrahim
Affiliations

Using the EM-algorithm for survival data with incomplete categorical covariates

S R Lipsitz et al. Lifetime Data Anal. 1996.

Abstract

Incomplete covariate data is a common occurrence in many studies in which the outcome is survival time. With generalized linear models, when the missing covariates are categorical, a useful technique for obtaining parameter estimates is the EM by the method of weights proposed in Ibrahim (1990). In this article, we extend the EM by the method of weights to survival outcomes whose distributions may not fall in the class of generalized linear models. This method requires the estimation of the parameters of the distribution of the covariates. We present a clinical trials example with five covariates, four of which have some missing values.

PubMed Disclaimer

References

    1. Am J Clin Oncol. 1990 Dec;13(6):510-5 - PubMed
    1. Am J Clin Oncol. 1995 Aug;18(4):287-92 - PubMed

Publication types