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. 1995;1(1):35-47.
doi: 10.1007/BF00985256.

Survival trees with time-dependent covariates: application to estimating changes in the incubation period of AIDS

P Bacchetti  1 , M R Segal
Affiliations

Survival trees with time-dependent covariates: application to estimating changes in the incubation period of AIDS

P Bacchetti et al. Lifetime Data Anal. 1995.

Abstract

Tree-structured methods for exploratory data analysis have previously been extended to right-censored survival data. We further extend these methods to allow for truncation and time-dependent covariates. We apply the new methods to a data set on incubation times of acquired immunodeficiency syndrome (AIDS), using calendar time as a time-dependent covariate. Contrary to expectation, we find that rates of progression to AIDS appear to be faster after August 1989 than before.

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