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Case Reports
. 1997 Oct;64(10):586-8.

Mesalazine-induced lupus

M A Timsit  1 , D Anglicheau, F Lioté, P Marteau, A Dryll
Affiliations
  • PMID: 9385697
Case Reports

Mesalazine-induced lupus

M A Timsit et al. Rev Rhum Engl Ed. 1997 Oct.

Abstract

We report a case of lupus induced by mesalazine therapy taken for over a year for Crohn's disease. The patient had polyarthritis, alopecia, lymphoneutropenia, antinuclear factors, anti-histone antibodies, anti-Sm and anti-RNP. Discontinuation of mesalazine was followed by rapid resolution of the joint manifestations, alopecia and lymphoneutropenia; the anti-histone antibodies fell to undetectable levels and the titers of the other auto-antibodies decreased gradually.

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