Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Jun;33(6):606-11.
doi: 10.1038/bjc.1976.98.

In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder

G Pizza, D Viza, C Boucheix, F Corrado
Free PMC article

In vitro production of a transfer factor specific for transitional-cell carcinoma of the bladder

G Pizza et al. Br J Cancer. 1976 Jun.
Free PMC article

Abstract

Human dialysable Transfer Factor (TFd) extracted from lymphocytes of patients with transitional cell carcinoma of bladder (TCCB) was replicated in culture by lymphoblastoid cell lines. The effectiveness of two such TFdLs produced in vitro in transferring sensitivity to TCCB was assessed in the lymphocyte migration test (LMT) using formalin-treated TCCB cells as antigen. The results, showed that one TFdL transferred sensitivity in 5/14 cases and the other in 12/15, not only to leucocytes of healthy individuals but also to leucocytes of TCCB patients. Preliminary results showing an in vivo transfer of sensitivity are discussed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Int J Cancer. 1972 Mar 15;9(2):417-25 - PubMed
    1. Lancet. 1973 May 19;1(7812):1085-8 - PubMed
    1. Lancet. 1973 Nov 10;2(7837):1087-8 - PubMed
    1. Int J Cancer. 1974 Sep 15;14(3):326-34 - PubMed
    1. J Clin Invest. 1975 Mar;55(3):487-99 - PubMed

Substances