Endometriosis in monozygotic twins

Abstract

Objective: To describe the occurrence of endometriosis in monozygotic twins.

Design: Postal questionnaire plus confirmation of disease status.

Setting: Twins were recruited via the American Endometriosis Association and the National Endometriosis Society of Great Britain and via British gynecologists.

Result(s): Fourteen twin pairs were concordant for endometriosis, and two were discordant. Nine pairs of twins had moderate-severe endometriosis.

Conclusion(s): These findings contribute to the growing body of literature that suggests endometriosis has a genetic basis.