The low frequency dynamic viscoelastic properties of human aortic valve tissue

Abstract

Membranous samples of human aortic valve cusps were subjected to sinusoidal fluid pressure variations (frequency range, 0.5-5 Hz) to assess their dynamic viscoelastic properties. The storage (elastic) and loss (viscous) moduli and phase lag between the stressing function and response were found to be independent of the frequencies applied. The respective average values were 1.35 (SE = 0.06) X 10(8) dynes cm-2, 4.14 (SE = 0.28) X 10(6) dynes cm-2, and 0.033 (SE = 0.002) rad. The small phase lag indicates that the tissue would recover almost completely to its original state on removal of any applied stress, and this and the relatively low extensibility should be considered in the design of leaflet-type valve prostheses. The storage modulus of the aortic valve cusps when compared to that of the mitral leaflet shows the mitral leaflet to be almost twice as stiff as the aortic valve cusps. This finding led us to conclude that the vibrations of these two cardiac valves alone cannot contribute in any significant way to the production of the observed lower frequency of the first and the higher frequency of the second heart sounds and that other factors must be considered to explain this finding.