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. 1976 Jul 7;33(1):61-6.
doi: 10.1007/BF00447287.

Gene dosage effect in human triploid fibroblasts

C Junien, H Rubinson, J C Dreyfus, M C Meinenhofer, N Ravise, J Boué, A Boué

Gene dosage effect in human triploid fibroblasts

C Junien et al. Hum Genet. .

Abstract

The activity of 13 cytoplasmic enzymes has been determined in fibroblast extracts from 9 triploid and 13 control lines. The results show a high activity for 2 X-linked enzymes, glucose 6-phosphate dehydrogenase and phosphoglycerate kinase. These data, together with cytogenetic observations, support the contention that 2 X chromosomes were active in the triploid lines.

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References

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