ATP synthase: an electrochemical transducer with rotatory mechanics
- PMID: 9397682
- DOI: 10.1016/s0968-0004(97)01129-8
ATP synthase: an electrochemical transducer with rotatory mechanics
Abstract
ATP synthase (F0F1-ATPase) uses proton- or sodium-motive force to produce ATP form ADP and P(i). Three lines of experiment have recently demonstrated large-scale intersubunit rotation during ATP hydrolysis by F1. We discuss how ion flow through the membrane-intrinsic portion, F0, may generate torque and how this might be transmitted between stator and rotor to finally expel spontaneously formed ATP from F1 into water.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous
