Effects of cryopreserved semen quality and timed intrauterine insemination on pregnancy rate and gender of offspring in a donor insemination program
- PMID: 9401872
- PMCID: PMC3454848
- DOI: 10.1023/a:1021131511209
Effects of cryopreserved semen quality and timed intrauterine insemination on pregnancy rate and gender of offspring in a donor insemination program
Abstract
Purpose: Our purpose was to study the relationship among cryopreserved donor semen quality, pregnancy rates, and preconception sex selection after intrauterine insemination.
Methods: We reviewed the records of the 203 women in our donor insemination program from 1987 to 1994 who became pregnant after more than one insemination cycle and had no female-factor infertility. They were categorized according to the number of cycles required for pregnancy. Semen samples from 54 donors were analyzed before freezing and after thawing. Specimens resulting in pregnancy were compared to specimens from the same donor that did not. Semen characteristics were compared to gender of the child.
Results: Two hundred fifty two-women became pregnant of the 422 who were enrolled. The pregnancy rate per cycle was 13%. Semen quality was not related to pregnancy outcome or offspring gender. However, more male children (101 vs 83) were born.
Conclusions: Semen characteristics in good-quality cryopreserved donor semen do not affect pregnancy rate or offspring gender.
Similar articles
-
Pregnancy rates with fresh versus computer-controlled cryopreserved semen for artificial insemination by donor in a private practice setting.Am J Obstet Gynecol. 1990 Jun;162(6):1483-8; discussion 1488-90. doi: 10.1016/0002-9378(90)90910-y. Am J Obstet Gynecol. 1990. PMID: 2360580
-
Therapeutic donor insemination with frozen semen.CMAJ. 1990 Aug 15;143(4):273-8. CMAJ. 1990. PMID: 2383847 Free PMC article.
-
Intrauterine insemination of cryopreserved donor semen.Fertil Steril. 1989 Aug;52(2):243-5. Fertil Steril. 1989. PMID: 2753173
-
Strategies in frozen donor semen procreation.Hum Reprod. 1995 Jul;10(7):1765-74. doi: 10.1093/oxfordjournals.humrep.a136171. Hum Reprod. 1995. PMID: 8582977 Review.
-
Artificial insemination with fresh donor semen.Arch Androl. 1990;25(2):173-9. doi: 10.3109/01485019008987608. Arch Androl. 1990. PMID: 2222080 Review.
Cited by
-
A low total motile sperm count in donor sperm obtained from commercial banks does not affect pregnancy rates from intrauterine insemination.Eur J Obstet Gynecol Reprod Biol X. 2023 Dec 9;21:100267. doi: 10.1016/j.eurox.2023.100267. eCollection 2024 Mar. Eur J Obstet Gynecol Reprod Biol X. 2023. PMID: 38111859 Free PMC article.
-
Predictive value of sperm motility characteristics assessed by computer-assisted sperm analysis in intrauterine insemination with superovulation in couples with unexplained infertility.Clin Exp Reprod Med. 2011 Mar;38(1):47-52. doi: 10.5653/cerm.2011.38.1.47. Epub 2011 Mar 31. Clin Exp Reprod Med. 2011. PMID: 22384418 Free PMC article.
References
-
- Gerber WL, Bresaw LS. Semen abnormalities in artificial insemination donor candidates. J Urol. 1983;130:266–268. - PubMed
-
- Nachtigall RD. Donor insemination and human immunodeficiency virus: A risk/benefit analysis. Am J Obstet Gynecol. 1994;170:1692–1696. - PubMed
-
- Schover LR, Thomas AJ, Miller KF, Falcone T, Goldberg J. Preferences for intracytoplasmic sperm injection versus donor insemination in severe male factor infertility: A preliminary report. Hum Reprod. 1996;11:2461–2464. - PubMed
-
- Vogt PH. Genetic aspects of artificial fertilization. Hum Reprod. 1995;10:128–137. - PubMed
-
- Carson SA. Sex selection: The ultimate in family planning. Fertil Steril. 1988;50:16–19. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources