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. 1997;21(2):79-85.
doi: 10.1023/a:1005848806641.

Indocyanine green angiographic findings in fellow eyes of patients with unilateral occult neovascular age-related macular degeneration

U Schneider  1 , F Gelisken, W Inhoffen, I Kreissig
Affiliations

Indocyanine green angiographic findings in fellow eyes of patients with unilateral occult neovascular age-related macular degeneration

U Schneider et al. Int Ophthalmol. 1997.

Abstract

Purpose: To determine the role of indocyanine green angiography (ICGA) in the prediction of the development of choroidal neovascularization (CNV).

Methods: We reviewed the ICG angiograms of 124 patients with newly diagnosed unilateral occult CNV secondary to age-related macular degeneration (AMD) in whom the fellow eye had only drusen by biomicroscopy and fluorescein angiography. Follow-up data of at least 12 months were obtained in all eyes.

Results: 113 fellow eyes had a normal ICG study, while 11 fellow eyes revealed plaque-like late hyperfluorescence. During an average follow-up time of 18.2 months exudative AMD developed in 7 of 11 eyes with late hyperfluorescence on ICGA and in 6 of 113 with a normal ICGA study.

Conclusion: ICGA may help to predict which fellow eyes are at higher risk of developing future exudative changes.

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