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. 1997 Nov;47(11):806-8.
doi: 10.1111/j.1440-1827.1997.tb04462.x.

'Ovarian-type' stroma of pancreatic mucinous cystic tumor expresses smooth muscle phenotype

N Fukushima, K Mukai

'Ovarian-type' stroma of pancreatic mucinous cystic tumor expresses smooth muscle phenotype

N Fukushima et al. Pathol Int. 1997 Nov.

Abstract

'Ovarian-type' stroma of nine mucinous cystic tumors (MCT) of the pancreas, six cystadenomas and three cystadenocarcinomas, were studied immunohistochemically. Most of the spindle cells of the 'ovarian-type' stroma were positive for smooth muscle actin and desmin, but were negative for S-100 protein, cytochrome P450 19 and CD34. Similar stroma with smooth muscle differentiation has been described in hepatobiliary MCT. Embryologic similarity between the pancreas and liver suggests a closely related origin of MCT in both organs.

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