Viral factors determining rotavirus pathogenicity
- PMID: 9413533
- DOI: 10.1007/978-3-7091-6534-8_13
Viral factors determining rotavirus pathogenicity
Abstract
The pathogenicity of rotaviruses depends on multiple viral and host factors. Evidence is presented for the involvement of a number of viral genes (coding for structural and non-structural proteins) in the ability of the virus to cause diarrhoea. Different genes are important in different rotavirus--host systems suggesting that there is no single viral pathogenicity factor.
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