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Review
. 1997:13:131-9.
doi: 10.1007/978-3-7091-6534-8_13.

Viral factors determining rotavirus pathogenicity

U Desselberger  1
Affiliations
Review

Viral factors determining rotavirus pathogenicity

U Desselberger. Arch Virol Suppl. 1997.

Abstract

The pathogenicity of rotaviruses depends on multiple viral and host factors. Evidence is presented for the involvement of a number of viral genes (coding for structural and non-structural proteins) in the ability of the virus to cause diarrhoea. Different genes are important in different rotavirus--host systems suggesting that there is no single viral pathogenicity factor.

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