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. 1998 Jan;177(1):209-12.
doi: 10.1086/517355.

Prior infection with cytomegalovirus is not a major risk factor for angiographically demonstrated coronary artery atherosclerosis

S P Adler  1 , J K Hur, J B Wang, G W Vetrovec
Affiliations

Prior infection with cytomegalovirus is not a major risk factor for angiographically demonstrated coronary artery atherosclerosis

S P Adler et al. J Infect Dis. 1998 Jan.

Abstract

To determine if cytomegalovirus (CMV) infection is a risk factor for primary coronary artery disease (CAD), the association between CMV infection and CAD (>50% blockage in any coronary artery) was investigated in nearly 900 successive nontransplant patients undergoing coronary angiography. By use of logistic regression, older age (P <.001), white race (P <.001), gender (P <.001), hypercholesterolemia (P = .04), and other established cardiovascular risk factors (P = .003) were identified as significantly associated with CAD, but CMV seropositivity (P = .462), the level of IgG antibodies to CMV whole cell antigen (P = .98), or the levels of IgG antibodies to CMV glycoprotein B (P = .67) were not. These data suggest that CMV infection is not a major risk factor for the development of primary CAD in adults.

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