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Clinical Trial
. 1997 Nov;12(8):486-8.
doi: 10.1177/088307389701200803.

Alpha-interferon in the treatment of subacute sclerosing panencephalitis

M N Fayad  1 , B I Yamout, S Mroueh
Affiliations
Clinical Trial

Alpha-interferon in the treatment of subacute sclerosing panencephalitis

M N Fayad et al. J Child Neurol. 1997 Nov.

Abstract

Subacute sclerosing panencephalitis is an inexorably progressive disease with no effective therapy. Recent trials of intrathecal and intraventricular alpha-interferon yielded controversial results. We tried intrathecal or intraventricular alpha-interferon in four patients with subacute sclerosing panencephalitis. None of them had evidence of improvement. We reviewed the previously published studies on the use of alpha-interferon in subacute sclerosing panencephalitis. Further international collaborative studies are needed to determine the role of alpha-interferon in the treatment of subacute sclerosing panencephalitis.

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