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. 1998 Jan;36(1):305-8.
doi: 10.1128/JCM.36.1.305-308.1998.

Results from 5 years of nationwide DNA fingerprinting of Mycobacterium tuberculosis complex isolates in a country with a low incidence of M. tuberculosis infection

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Results from 5 years of nationwide DNA fingerprinting of Mycobacterium tuberculosis complex isolates in a country with a low incidence of M. tuberculosis infection

J Bauer et al. J Clin Microbiol. 1998 Jan.

Abstract

Results from DNA fingerprint analyses of Mycobacterium tuberculosis complex isolates from tuberculosis (TB) patients diagnosed during 5 years in Denmark are presented. The lack of success in eradicating TB in this low-incidence country may be explained by an unrecognized high frequency of active TB transmission (57%) among native Danes. Only two strains of M. tuberculosis are responsible for 40% of all clustered cases of TB among Danes.

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Figures

FIG. 1
FIG. 1
Frequency of case clustering among Danes, grouped by age and gender (A) or by age and residence (B), from 1992 to 1996.
FIG. 2
FIG. 2
Number of patients with RFLP-analyzed TB isolates and incidence of notified cases.
FIG. 3
FIG. 3
Map of Denmark showing the geographical distribution of patients infected with M. tuberculosis strains belonging to the two most frequent clusters. Triangles, cluster 1; circles, cluster 2. Numbers represent cases.

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