[Uterine metastasis of invasive lobular breast carcinoma. Case report and review of the literature with reference to differential diagnostic problems and clinical consequences]

Abstract

Uterine metastases of malignant tumours are rare. Among extragenital malignancies breast cancers of the lobular type most likely spread out to this site. The respective diagnosis is rendered more difficult by the late onset of clinical symptoms that may imitate the picture of primary uterine cancer. We report on a patient with advanced invasive lobular breast cancer (ILC) where this form of metastazation was detected after conization for PAP IVa. Especially in patients with advanced lobular breast cancer and suspicious symptoms (such as pathologic PAP-Smear, conspicuous colposcopic finding, vaginal bleeding, growth-progressive uterus and hyperplastic endometrium) the possibility of uterine metastases should be included in preoperative planning.