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Comparative Study
. 1979 Nov;45(2):301-8.
doi: 10.1099/0022-1317-45-2-301.

Priming increases the amount of interferon mRNA in poly(rI).poly(rC)-treated L cells

Comparative Study

Priming increases the amount of interferon mRNA in poly(rI).poly(rC)-treated L cells

T Fujita et al. J Gen Virol. 1979 Nov.

Abstract

Priming by mouse interferon pre-treatment resulted in an accumulation of interferon mRNA in poly(rI).poly(rC)-treated L cells, starting early in the period of interferon synthesis. On electrophoresis, the priming activity of an interferon preparation co-migrated with the antiviral activity, which suggests identity of the functional principle(s) for these activities.

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