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Case Reports
. 1997 Nov-Dec;14(6):477-9.
doi: 10.1111/j.1525-1470.1997.tb00695.x.

Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient

S Menni  1 , G Pistritto, R Gianotti, L Ghio, A Edefonti
Affiliations
Case Reports

Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient

S Menni et al. Pediatr Dermatol. 1997 Nov-Dec.

Abstract

We describe a bullous-hemorrhagic reaction of the ear lobes in a child with nephrosis after levamisole intake. This drug is used in children as an alternative treatment of corticosteroid-responsive nephrotic syndrome. Histologic evaluation of a lesion revealed necrotizing vasculitis involving mainly the large vessels of the deep plexus. The lesions disappeared 25 days after discontinuation of treatment.

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