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. 1976 Mar 11;260(5547):116-20.
doi: 10.1038/260116a0.

Injected nuclei in frog oocytes provide a living cell system for the study of transcriptional control

J B Gurdon, E M De Robertis, G Partington

Injected nuclei in frog oocytes provide a living cell system for the study of transcriptional control

J B Gurdon et al. Nature. .

Abstract

Human HeLa nuclei injected into Xenopus oocytes synthesise RNA continuously for up to 1 month, and some of this RNA is translated into HeLa proteins. Nuclear proteins extracted from other cells enter the injected nuclei. This living cell system can be used for the study of transcriptional controls.

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