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. 1976 Feb;13(1):11-4.
doi: 10.1002/tera.1420130103.

Prenatal effects of Ochratoxin A in hamsters

R D Hood, M J Naughton, A W Hayes

Prenatal effects of Ochratoxin A in hamsters

R D Hood et al. Teratology. 1976 Feb.

Abstract

Pregnant golden hamsters were injected ip with 2.5-20 mg/kg ochratoxin A on one of gestation days 7-10. The largest dosages when given on day 7,8, or 9 increased prenatal mortality and on day 9 diminished fetal growth. Malformations, such as micrognathia, hydrocephalus, short tail, oligodactyly, syndactyly, cleft lip, micromelia, and heart defects occurred, but no skeletal malformations were noted. These results add to the prenatal effects of ochratoxin A previously reported in mouse, rat, and chicken embryos.

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