Review
doi: 10.1146/annurev.cellbio.13.1.53.
Left-right asymmetry in animal development
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- PMID: 9442868
- DOI: 10.1146/annurev.cellbio.13.1.53
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Review
Left-right asymmetry in animal development
Annu Rev Cell Dev Biol.
1997.
Abstract
Most animal species exhibit left-right asymmetry in their body plans and show a strong bias for one handedness over the other. The mechanism of handedness choice, recognized as an intriguing problem over a century ago, is still a mystery. However, from recent advances in understanding when and how asymmetry arises in both invertebrates and vertebrates, developmental pathways for establishment and maintenance of left-right differences are beginning to take shape, and speculations can be made on the initial choice mechanism.
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