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Review
. 1997 Dec;20(4):723-39.
doi: 10.1016/s0193-953x(05)70342-7.

Serotonergic systems

Affiliations
Review

Serotonergic systems

F G Graeff. Psychiatr Clin North Am. 1997 Dec.

Abstract

Since its identification in neurons of the central nervous systems (CNS), serotonin (5-HT) has been implicated in the pathophysiology of psychiatric disorders, such as schizophrenia, depression, generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD). These findings have stimulated research on brain 5-HT pathways, especially during the last two decades as more selective drugs have been introduced into medical practice. This article reviews selected topics relevant for psychiatry.

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