Sydenham's chorea
- PMID: 9443351
- DOI: 10.1016/s0193-953x(05)70346-4
Sydenham's chorea
Abstract
Sydenham's chorea (SC) is a disorder of the central nervous system (CNS) characterized by sudden, involuntary, arrhythmic, clonic, and purposeless movements. SC appears to provide a model for understanding various neuropsychiatric dysfunctions. Its relationship with attentional deficits, obsessive-compulsive symptoms (OCS) as well as movement disorders provides support for the hypothesis of the involvement of the corticostriatal loops in the pathophysiology of the disorder.
Similar articles
-
Neuropsychiatric aspects of Sydenham's chorea: a comprehensive review.J Clin Psychiatry. 1996 Sep;57(9):407-14. J Clin Psychiatry. 1996. PMID: 9746449 Review.
-
High prevalence of obsessive-compulsive symptoms in patients with Sydenham's chorea.Am J Psychiatry. 1989 Feb;146(2):246-9. doi: 10.1176/ajp.146.2.246. Am J Psychiatry. 1989. PMID: 2912267
-
Obsessive-compulsive and related symptoms in children and adolescents with rheumatic fever with and without chorea: a prospective 6-month study.Am J Psychiatry. 1998 Aug;155(8):1122-4. doi: 10.1176/ajp.155.8.1122. Am J Psychiatry. 1998. PMID: 9699708
-
Sydenham's chorea: not gone and not forgotten.Semin Pediatr Neurol. 2003 Mar;10(1):11-9. doi: 10.1016/s1071-9091(02)00004-9. Semin Pediatr Neurol. 2003. PMID: 12785743 Review.
-
The psychiatric symptoms of rheumatic fever.Am J Psychiatry. 2000 Dec;157(12):2036-8. doi: 10.1176/appi.ajp.157.12.2036. Am J Psychiatry. 2000. PMID: 11097972
Cited by
-
Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease.J Immunol. 2013 Dec 1;191(11):5524-41. doi: 10.4049/jimmunol.1102592. Epub 2013 Nov 1. J Immunol. 2013. PMID: 24184556 Free PMC article.
-
Is obsessive-compulsive disorder an autoimmune disease?CMAJ. 2001 Nov 13;165(10):1353-8. CMAJ. 2001. PMID: 11760984 Free PMC article. Review.
-
Therapeutic aspects of Sydenham's Chorea: an update.Acta Biomed. 2022 Mar 21;92(S4):e2021414. doi: 10.23750/abm.v92iS4.12663. Acta Biomed. 2022. PMID: 35441610 Free PMC article. Review.
-
Mice repeatedly exposed to Group-A β-Haemolytic Streptococcus show perseverative behaviors, impaired sensorimotor gating, and immune activation in rostral diencephalon.Sci Rep. 2015 Aug 25;5:13257. doi: 10.1038/srep13257. Sci Rep. 2015. PMID: 26304458 Free PMC article.
-
Disruption of the blood-brain barrier contributes to neurobehavioral changes observed in rheumatic heart disease.Animal Model Exp Med. 2025 Jun;8(6):1138-1145. doi: 10.1002/ame2.70012. Epub 2025 Mar 10. Animal Model Exp Med. 2025. PMID: 40059805 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources