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. 1976 Jan;4(1):111-4.
doi: 10.1016/0091-3057(76)90184-2.

Effects of chlorpromazine on avoidance and escape responding in humans

M W Fischman, R C Smith, C R Schuster

Effects of chlorpromazine on avoidance and escape responding in humans

M W Fischman et al. Pharmacol Biochem Behav. 1976 Jan.

Abstract

The effects of chlorpromazine on shock avoidance and escape responding were determined using four human subjects lever pressing on a modified free operant avoidance schedule. Doses of chlorpromazine ranging from 50 to 100 mg and shock levels ranging from 0.35 to 3.0 mA were used. In general, the results showed that chlorpromazine suppressed avoidance responding at doses which did not suppress escape responding.

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