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. 1976 Feb;11(2):319-29.
doi: 10.1016/0090-6980(76)90154-4.

Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F during pregnancy in sheep

M D Mitchell, A P Flint, A C Turnbull

Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F during pregnancy in sheep

M D Mitchell et al. Prostaglandins. 1976 Feb.

Abstract

A specific and sensitive radioimmunoassay is decribed for 13,14-dihydro-15-keto-prostaglandin F in ovine plasma. Using this assay it has been shown that, in sheep, jugular venous 13,14-dihydro-15-keto-prostaglandin F concentrations increase at parturition and correlate well with concentrations of prostaglandin F in the utero-ovarian vein. It is suggested that uterine prostaglandin F production under these conditions may be assessed by measuring peripheral venous 13,14-dihydro-15-keto-prostaglandin F, thereby avoiding the need for chronic utero-ovarian venous catheters.

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