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. 1997 Oct;40(4):527-30.

Acute myelofibrosis

S Das  1 , B R Prabhakar
Affiliations
  • PMID: 9444866

Acute myelofibrosis

S Das et al. Indian J Pathol Microbiol. 1997 Oct.

Abstract

Acute myelofibrosis is a rare disorder. Five such cases have been diagnosed out of 3,149 Bone Marrow (B.M) Aspirations and Trephine Biopsies studied over a period of eight and a half years. Four out of five patients were males and the other female. Their age ranged from 14-71 years. Neither splenomegaly not red cell poikilocytosis (tear drop cells) were prominant features. B.M. trephine biopsy showed increase of atypical megakaryocytes/megakaryoblasts and marked fibrosis. There was rapid downhill clinical course of the disease in all cases.

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