Pulmonary blastoma: case report of a patient with a 7-year remission and review of chemotherapy experience in the world literature

Abstract

Background: Pulmonary blastoma is a rare malignant neoplasm for which there currently are no treatment guidelines.

Methods: A patient with locally advanced pulmonary blastoma is described. The treatment modality is discussed and the world literature is reviewed with respect to the use of chemotherapy.

Results: A 54-year-old man had a 7-year disease free survival despite subtotal resection. He was treated with adjuvant radiotherapy and combination chemotherapy. Three cycles of cisplatin and etoposide were administered. The world literature was reviewed with regard to the use of adjuvant chemotherapy in the treatment of pulmonary blastoma.

Conclusions: Surgery, adjuvant radiotherapy, and combination chemotherapy with cisplatin and etoposide should be considered in the treatment of patients with this rare pulmonary neoplasm.