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Review
. 1998 Mar:111 ( Pt 5):541-7.
doi: 10.1242/jcs.111.5.541.

Tight junctions

M S Balda  1 , K Matter
Affiliations
Review

Tight junctions

M S Balda et al. J Cell Sci. 1998 Mar.

Abstract

Tight junctions are the most apical intercellular junctions of epithelial and endothelial cells and create a regulatable semipermeable diffusion barrier between individual cells. On a cellular level, they form an intramembrane diffusion fence that restricts the intermixing of apical and basolateral membrane components. In addition to these well defined functions, more recent evidence suggests that tight junctions are also involved in basic cellular processes like the regulation of cell growth and differentiation.

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