doi: 10.1016/s0197-0186(97)00039-9.
Regulated release of serotonin from axonal growth cones isolated from the fetal rat brain
Affiliations
- PMID: 9460708
- DOI: 10.1016/s0197-0186(97)00039-9
Item in Clipboard
Regulated release of serotonin from axonal growth cones isolated from the fetal rat brain
Neurochem Int.
1998 Jan.
Abstract
In the present work we propose an hypothetical model related to a molecular recognizing system for serotonin in isolated growth cone particles. This model is supported by previous results from our laboratory plus new ones which show that growth cones release serotonin tonically and such release can be stimulated by potassium in a calcium-dependent manner. The present results, together with other author's data, suggest a physiological basis for the putative role of serotonin as a trophic factor during nervous system development.
Similar articles
-
[Serotonin as a neurotrophic factor in the fetal brain: binding, capture and release in centers of axonal growth].Gac Med Mex. 1994 Jul-Aug;130(4):246-52. Gac Med Mex. 1994. PMID: 8964332 Spanish.
-
Regulated plasmalemmal expansion in nerve growth cones.J Cell Biol. 1991 Mar;112(6):1215-27. doi: 10.1083/jcb.112.6.1215. J Cell Biol. 1991. PMID: 1999470 Free PMC article.
-
A molecular recognizing system of serotonin in rat fetal axonal growth cones: uptake and high affinity binding.Brain Res Dev Brain Res. 1992 Sep 18;69(1):133-7. doi: 10.1016/0165-3806(92)90130-o. Brain Res Dev Brain Res. 1992. PMID: 1424085
-
Developmental changes in the calcium dependency of gamma-aminobutyric acid release from isolated growth cones: correlation with growth cone morphology.J Neurochem. 1989 Sep;53(3):834-43. doi: 10.1111/j.1471-4159.1989.tb11780.x. J Neurochem. 1989. PMID: 2760622
-
Axonal origin and purity of growth cones isolated from fetal rat brain.Brain Res Dev Brain Res. 1996 Oct 23;96(1-2):83-96. doi: 10.1016/0165-3806(96)00076-4. Brain Res Dev Brain Res. 1996. PMID: 8922671
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
