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. 1998 Jan;61(1):34-9.
doi: 10.1021/np9703252.

Three new bistetrahydrofuran acetogenins from the seeds of Annona spinescens

E F Queiroz  1 , F Roblot, B Figadère, A Laurens, P Duret, R Hocquemiller, A Cavé, L Serani, O Laprévote, J Cotte-Laffitte, A M Quéro
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Three new bistetrahydrofuran acetogenins from the seeds of Annona spinescens

E F Queiroz et al. J Nat Prod. 1998 Jan.

Abstract

Three new bistetrahydrofuran acetogenins, carolins A-C (1-3), were isolated from the MeOH extract of Annona spinescens in addition to the known compound, squamocin (4). The structures of 1, 2, and 3 were elucidated by spectroscopic methods including LSIMS/MS technique and confirmed by a chemical transformation, The cytotoxic activity of the new compounds 1-3 is reported and discussed in comparison with 4 and the previously isolated spinencin (5).

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