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. 1997 Sep-Oct;91(5):592-3.
doi: 10.1016/s0035-9203(97)90040-7.

Reduced Loa loa microfilaria count ten to twelve months after a single dose of ivermectin

T H Duong  1 , M Kombila, A Ferrer, P Bureau, P Gaxotte, D Richard-Lenoble
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Reduced Loa loa microfilaria count ten to twelve months after a single dose of ivermectin

T H Duong et al. Trans R Soc Trop Med Hyg. 1997 Sep-Oct.

Abstract

The action of a single dose of ivermectin (200 micrograms/kg) on 71 Gabonese patients with Loa loa microfilariae in the peripheral blood, and living in areas highly endemic for loiasis, has been evaluated. Ten to 12 months after treatment, 43 patients (63%) had no circulating microfilaria and the geometric mean peripheral blood microfilaria count had decreased by 88.6% (P < 0.02). Thus, a single annual dose of ivermectin can markedly reduce loiasis transmission.

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