Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Jun;100(6):329-33.

Rectal suction biopsy in the diagnosis of Hirschsprung disease in infants

E J Yunis, A W Dibbins, F E Sherman
  • PMID: 946762

Rectal suction biopsy in the diagnosis of Hirschsprung disease in infants

E J Yunis et al. Arch Pathol Lab Med. 1976 Jun.

Abstract

Our experience with 47 rectal suction biopsies performed in infants up to six months of age indicates that this is a simple and effective method for the exclusion of Hirschsprung disease. It requires the recognition of immature ganglion cells in neural units as equivalent to mature ganglion cells. Absence of these immature neural units in an adequate sample is highly suggestive of Hirschsprung disease.

PubMed Disclaimer