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Review
. 1997 Nov;62(11):1323-31.

Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review

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  • PMID: 9467857
Review

Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review

A K Meeker et al. Biochemistry (Mosc). 1997 Nov.

Abstract

This review will describe the current state of knowledge of telomerase as it relates to human malignancies, focusing primarily on published measurements of this enzymes activity in benign and malignant neoplasms and their normal tissue counterparts. Key questions concerning the potential clinical utility of assaying for telomerase activity will be addressed and the implications of recent findings discussed.

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