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Comparative Study
. 1979 Oct;14(4):309-16.
doi: 10.1111/j.1399-0039.1979.tb00854.x.

Two HLA-D and DR alleles are associated with coeliac disease

M DeMarchi, I Borelli, E Olivetti, P Richiardi, P Wright, N Ansaldi, C Barbera, B Santini
Comparative Study

Two HLA-D and DR alleles are associated with coeliac disease

M DeMarchi et al. Tissue Antigens. 1979 Oct.

Abstract

A group of 45 children affected with Coeliac Disease (CD) was typed for HLA-A, B, C, D, and DR specificities. The most significant associations were found with two alleles of the D series, with both cellular and serological typing. It is suggested that the susceptibility to CD is determined by two different genes within the HLA region, the first in common with organ-specific autoimmune diseases and associated with DW3, the second possibly specific for CD and associated with Dw7.

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