Comment on

• An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction.

  GUSTO investigators. GUSTO investigators. N Engl J Med. 1993 Sep 2;329(10):673-82. doi: 10.1056/NEJM199309023291001. N Engl J Med. 1993. PMID: 8204123 Clinical Trial.
• A comparison of continuous infusion of alteplase with double-bolus administration for acute myocardial infarction.

  Continuous Infusion versus Double-Bolus Administration of Alteplase (COBALT) Investigators. Continuous Infusion versus Double-Bolus Administration of Alteplase (COBALT) Investigators. N Engl J Med. 1997 Oct 16;337(16):1124-30. doi: 10.1056/NEJM199710163371604. N Engl J Med. 1997. PMID: 9340504 Clinical Trial.