Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1998 Jan-Feb;5(1):3-28.

Suppression of growth and transformation and induction of apoptosis by EGR-1

C Liu  1 , V M Rangnekar, E Adamson, D Mercola
Affiliations
  • PMID: 9476963
Review

Suppression of growth and transformation and induction of apoptosis by EGR-1

C Liu et al. Cancer Gene Ther. 1998 Jan-Feb.

Abstract

Although cloned as an "immediate-early gene," recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor beta-1 (TGF-beta1) gene and cooperation with Sp1, Jun-B, p21WAF1/Cip1, and stimulates apoptosis by transactivation of the p53 gene.

PubMed Disclaimer

Publication types

LinkOut - more resources